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The most frequently reported adverse effects were gastrointestinal in nature, generally mild to moderate in severity and transient, typically occurring during the dose-escalation period

Furthermore, dietary supplementation with 1% or 2% glycine prevented the occurrence of submucosal and lamina propria hemorrhages in the proximal intestine of Phase-I HSB (weighing 5 to 40 g) [13], while improving the intestinal structure of both Phase-I HSB and Phase-II HSB (weighing 110 to 240 g) [14]

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